The objective of this study was to examine the effect of personality factors namely risk taking, need for achievement, and locus of control as well as environmental support towards the entrepreneurial motives of students at State Islamic College in Indonesia. A total number of 372 undergraduate students were selected using cluster-sampling technique for the investigation. The data were analyzed using Structural Equation Modeling (SEM) with risk taking, need for achievement, and locus of control as exogenous variables and environmental support and entrepreneurial motive as endogenous variable. The findings have shown that there was a significant effect of risk taking, need for achievement, and locus of control on the environmental support and environmental support mediated between students’ personality and their entrepreneurial motives. Implication, limitation and suggestion for future research are discussed.